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Notes on: The key role of mitochondrial function in health and disease part 4

Part 4. Let’s do this. Something to quickly note from Andy Galpin’s lactate performance lecture. When drinking alcohol you metabolize ethanol with anaerobic glycolysis. This downregulates fat metabolism. Normally the fat stored in the liver would be metabolized, but since you have placed ethanol ahead of it in the metabolism cue, liver fat accumulates. When […]

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Notes on: The key role of mitochondrial function in health and disease part 3

Here we go! Part 3 of this review paper written by Inigo San-Millan. This post will explore some of the bioenergetics of mitochondria. Mitochondria burn (oxidize) energy from macronutrients through oxidative phosphorylation that occurs in the Krebs cycle. Mitochondria oxidize all major substrates derived from macronutrients. Mitochondria oxidizes pyruvate from carbohydrates, fatty acids derived from

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Notes on: The key role of mitochondrial function in health and disease part 2

Hello there! We continue this note series on this review paper written by Iñigo San-Millán. The cell nucleus contains genes encoding for about 1200 proteins involved in:⦁ Mitochondrial structure⦁ Membrane⦁ Mitochondrial DNA (mtDNA) repair Nuclear DNA – The DNA found in the cell’s nucleus. Mitochondrial DNA – The DNA found in the mitochondria. “Nuclear DNA

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Notes on: The key role of mitochondrial function in health and disease part 1

The following notes are from this review paper written by Iñigo San-Millán. Enjoy! Resting conditions (fatty acids & carbohydrates) — Transported — > mitochondria –> oxidized to Acetyl-CoA –> Posterior oxidation in the Krebs cycle and electron transport chain (ETC) <– This is called oxidative phosphorylation (OXPHOS) –> creates Adenosine triphosphate (ATP) energy currency of

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Everything about vitamin D (Well, not everything, but it’s a lot)

Introduction Known as the ‘English Disease’, rickets, or for adults, osteomalacia, is a vitamin deficiency disease that causes the softening of bone. It was discovered in the early twentieth century that the cure to rickets was a newly discovered vitamin, called vitamin D1. Vitamin D functions in calcium and phosphorus absorption from the gastrointestinal tract.

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Origin story

My aim with this blog post is to document a little bit of my origin story and training approach that led me to back to back 11-minute personal records (PRs) at the Richmond Marathon in 2023 (2:52:47) and just recently at Richmond 2024 (2:41:00). Spoiler alert: I couldn’t have accomplished anything without the great gifts

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DIY Zero Cost Running Form Analysis

There is a consensus that running biomechanics influences the risk of developing running-related injuries. Treadmill form has been shown to closely resemble overground running form. This makes it possible to use a treadmill form analysis as a proxy for understanding overground running form. It’s quick, easy, cheap, and can help generate some serious insight into

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